Digital Module 05: Diagnostic Measurement—The G‐DINA Framework https://ncme.elevate.commpartners.com     

Wenchao Ma  Jimmy de la Torre 《Educational Measurement》2019,38(2):114-115

In this ITEMS module, we introduce the generalized deterministic inputs, noisy “and” gate (G‐DINA) model, which is a general framework for specifying, estimating, and evaluating a wide variety of cognitive diagnosis models. The module contains a nontechnical introduction to diagnostic measurement, an introductory overview of the G‐DINA model, as well as common special cases, and a review of model‐data fit evaluation practices within this framework. We use the flexible GDINA R package, which is available for free within the R environment and provides a user‐friendly graphical interface in addition to the code‐driven layer. The digital module also contains videos of worked examples, solutions to data activity questions, curated resources, a glossary, and quizzes with diagnostic feedback.  相似文献   

Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)     

Fadhaa A. Ghafil  Bassim I. Mohammad  Hussain S. Al-Janabi  Najah R. Hadi  Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.  相似文献   

重庆市主城区降雨侵蚀力特征分析   总被引：6，自引：0，他引：6  

缪驰远  徐霞  魏欣  曾宪勤 《资源科学》2007,29(4):54-60

文章根据重庆市自建气象站以来的降雨过程资料(1954～2001)，对重庆市主城区降雨侵蚀力(R)及其特征进行了研究和分析。研究结果表明，研究区降雨侵蚀力主要集中在5月～9月，48年里研究区年降雨侵蚀力值变幅均较大，但从整体上来看，趋势保持平稳，其离差系数Cv和变化趋势系数r值分别为0.65和0.061； 研究区次降雨量与次降雨侵蚀力，月降雨量与月降雨侵蚀力均呈乘幂关系，而年降雨量与年降雨侵蚀力呈现指数关系； 为了解决在降雨资料不足的情况下对降雨侵蚀力的计算，文章利用不同的降雨资料与侵蚀力之间进行相关分析，最终确定了适合研究区的两种降雨侵蚀力简易算法。  相似文献   

四川象牙参属二新种     

祝正银 《中国科学院研究生院学报》1988,26(4):315-317

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Contests for cooperation—A new approach in German innovation policy     

Alexander Eickelpasch  Michael Fritsch 《Research Policy》2005,34(8):1269-1282

A new approach in German innovation policy organizes contests of proposals for developing innovation networks. Based on an overview of the different programs, we investigate the advantages and problems of such an approach. We find that this type of policy may have a relatively large impact and can, therefore, be regarded as a rather efficient instrument of innovation policy. Compared to conventional policies, administration of the program is a much more critical issue. The contest approach may stimulate learning effects on the side of the administration but may also require a high degree of flexibility. The main disadvantage is the additional time that is required for conducting the contest. As a distinct ‘picking the winner’ approach, the contest approach is not suited as a means for achieving a leveling-out of regional welfare.  相似文献   

不同的分组方法对赫斯特指数的影响     

梁静溪  陈昭 《中国软科学》2004,(9):135-139

赫斯特指数的计算过程需要对研究的时间序列数据进行分组,而不同的分组情况对赫斯特指数会产生不同的影响。以深圳股票市场1997-2001年的日收盘成分指数为例,表明组内数据为15个左右时计算的赫斯特指数的可信度较高,但不同的分组方法却不会使结论发生质的变化,仅是量的改变。  相似文献   

论费曼的人生哲学     

解世雄 《嘉应学院学报》2008,26(4)

费曼作为最杰出的物理学大师之一,他不仅对物理理论做出了杰出的贡献,对科学文化的传播也有独特的贡献。费曼生活方式的核心就是要让自己愉快;他生性乐观,洒脱,幽默,兴趣广泛,从不压抑自己,敢于讲真话,因而,深受同事和学生的爱戴。本文从费曼人生哲学形成的文化背景出发,深入发掘他包含了自由、好奇、热情、正直的人生观,以展示费曼丰富多彩的科学智慧对我国知识分子的启示。  相似文献   

诺和锐30特充对2型糖尿病患者血浆C-反应蛋白的影响     

邵海琳  何峰  林展增 《河北北方学院学报(医学版)》2007,24(5):25-26

目的：观察诺和锐30特充对2型糖尿病患者血浆C-反应蛋白的影响。方法：选择80例2型糖尿病病人,随机分为诺和锐治疗组及诺和灵30R治疗组,诺和锐为餐前即刻皮下注射,诺和灵30R为餐前30min皮下注射,观察两组病人治疗前后餐前、餐后血糖及血浆C-反应蛋白（C-reactive protein,CRP）情况。结果：诺和锐治疗组餐后血糖水平低于诺和灵30R组（P〈0.01）,诺和锐治疗组治疗后C反应蛋白水平明显低于诺和灵30R治疗组（P〈0.01）。结论：对于2型糖尿病患者,诺和锐疗效优于诺和灵30R,而且可以显著降低血浆CRP的水平。  相似文献   

R290在家用空调中替代R22的实验研究     

刘丽刚 《顺德职业技术学院学报》2007,5(4):26-28

为探索R290作为制冷剂在家用空调中应用的可行性,在相同型号的空调器中进行了R290与R22的性能对比实验。结果表明:家用空调器不仅可以用R290替代R22,而且还有环保和节能的效果,能效比可提高10.26%～19.53%。  相似文献   

Performance of Montessori and traditionally schooled nursery children on tasks of seriation, classification, and conservation     

Jacqueline M. White  Steven R. Yussen  Edward M. Docherty 《Contemporary educational psychology》1976,1(4):356-368

It was hypothesized that the Montessori curriculum accelerates the acquisition of a number of concrete operational skills. To test this, eighty 4-year-old children were given three Piagetian problems—seriation, classification, and conservation. Half of the subjects were from Montessori schools, and the other half were from more traditional nursery settings. Within each type of school, half of the children were first year and the other half were second year enrollees. Results showed that significantly more Montessori than traditional children seriated and classified objects like concrete thinkers but that there were no differences on the conservation problem. Year of enrollment did not influence performance on any of the tasks. It was concluded that the hypothesis was confirmed and that the failure to find acceleration of conservation performance was due to its advanced nature relative to the other problems and/or the tangential manner in which Montessori exercises deal with the critical concepts that underly it.  相似文献